Telemedicine has become an accepted technology with multiple firms able to provide live video consults with physicians, often presented by companies as a benefit for their employees. The next frontier is to explore specialty services which are using this same technology and are solving major medical problems on a worldwide basis. Patients in El Salvador are having remote retinal exams to predict instances of diabetes. Second Opinions which require the assembling of multiple data types (medical records, images, video) are being sent from under-privileged countries with the purpose of providing patients with expert medical advice. Brand new technology is enabling the review of pap smears from third world countries to determine if patients in under-served areas are likely to have cervical cancer. Teleradiology, which was the first widely accepted form of telemedicine is now being enhanced with machine learning to improve the radiologist's capability to detect tumors with increased accuracy. These developments will be presented as brief case studies exploring the potential as well as the obstacles.